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HMR lab

at the High Field NMR Center in Lyon

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About HMR Lab

Our research interests are centered around the development of new hyperpolarization approaches for preparing nuclear spins in highly polarized ‘or aligned’ states, typically yielding > 10’000 fold sensitivity enhancements in magnetic resonance (both NMR and MRI).


To put it simple we magnetize molecules and materials to augment their sensitivity in magnetic resonance.


We are spanning across disciplines, from Physics, Chemistry, Biochemistry, to Medicine. We conceive new methods and instrumentation, and ultimately provide powerful tools to solve challenges at the forefront of molecular and chemical sciences today.

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Housekeeping Meeting at CRMN

October 2019


Job Offers

We are seeking for Master, PhD and Post Doc candidates

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Postdoc in methods development

A Postdoctoral position is available working on a project funded by the European Research Council.

The candidate will work on two projects:

  • Hyperpolarization transport (ERC StG HP4all) - low temperature DNP experiments with a functional state-of-the-art polarizer, using novel hyperpolarizing materials that are synthetized in our team and that extend the lifetime of hyperpolarized MRI tracers to days and transport of hyperpolarized samples to a preclinical MRI facility.

  • Replenishable hyperpolarization by rapid-cycle DNP (ERC CoG HypFlow). Participation in the development and applications of a new rapid-cycle DNP setup in which samples are repeatedly frozen, polarized, melted and circulated to a flow NMR system.

Master Internship Position 

Méthodes en RMN ‘hyperpolarisées’ et préparation d’agents de contraste IRM.


We are looking for candidates with background in Physics or Chemistry.

Research Engineer position

​We are looking for candidates with:

  • PhD in NMR

  • interest in liquid state NMR and dissolution DNP;

  • strong scientific background;

Our Team

Home: Membres de l'Équipe
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Chloé Gioiosa

PhD Student

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Charlotte Bocquelet

PhD Student

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Quentin Chappuis

Postdoc

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Sylvie Guibert

Staff Scientist

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James Tolchard

NMR Staff Scientist

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Sami Jannin

Professor at the Lyon 1 University
Deputy Director of CRMN
Head of HMRLab

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Nathan Rougier

Engineer

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Ewoud Vaneeckhaute

Postdoc

Former members

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Olivier Cala

Former NMR Staff Scientist (2017-2022)

Chemistry Teacher now

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Selected Publications

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Transporting hyperpolarization

January 1st, 2017

Nature Communications

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HYBRID POLARIZING SOLIDS

October 14, 2014

Proceeding of the National Academy of Science of the USA

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CROSS-POLARIZATION assisted d-DNP

December 7, 2012

Journal of Physical Chemistry Letters

Selected Posters

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A. Ferrari

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HYP20 Conference

..about a new generation of unstructured HYPSO materials yielding >95% proton polarization...

O. Cala

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HYP20 Conference

...about a hyperpolarization ready chemical library for drug screening...

T. El. Darai

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HYP20 Conference

...about how porous polarizing polymers can generate transportable hyperpolarization...

Main On-going Grants

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Project on Hyperpolarization Transport

ERC Starting Grant - HP4all

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