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HMR lab
at the High Field NMR Center in Lyon
About HMR Lab
Our research interests are centered around the development of new hyperpolarization approaches for preparing nuclear spins in highly polarized ‘or aligned’ states, typically yielding > 10’000 fold sensitivity enhancements in magnetic resonance (both NMR and MRI).
To put it simple we magnetize molecules and materials to augment their sensitivity in magnetic resonance.
We are spanning across disciplines, from Physics, Chemistry, Biochemistry, to Medicine. We conceive new methods and instrumentation, and ultimately provide powerful tools to solve challenges at the forefront of molecular and chemical sciences today.
Housekeeping Meeting at CRMN
October 2019
Postdoc in methods development
A Postdoctoral position is available working on a project funded by the European Research Council.
The candidate will work on two projects:
Hyperpolarization transport (ERC StG HP4all) - low temperature DNP experiments with a functional state-of-the-art polarizer, using novel hyperpolarizing materials that are synthetized in our team and that extend the lifetime of hyperpolarized MRI tracers to days and transport of hyperpolarized samples to a preclinical MRI facility.
Replenishable hyperpolarization by rapid-cycle DNP (ERC CoG HypFlow). Participation in the development and applications of a new rapid-cycle DNP setup in which samples are repeatedly frozen, polarized, melted and circulated to a flow NMR system.
Master Internship Position
Méthodes en RMN ‘hyperpolarisées’ et préparation d’agents de contraste IRM.
We are looking for candidates with background in Physics or Chemistry.
Research Engineer position
We are looking for candidates with:
PhD in NMR
interest in liquid state NMR and dissolution DNP;
strong scientific background;
We are glad to annonce that the HYP21 conference will be held in Lyon in 2021
Our Team
Charlotte Bocquelet
PhD Student
Quentin Chappuis
PhD Student
Sami Jannin
Professor at the Lyon 1 University
Deputy Director of CRMN
Head of HMRLab
Former members
Aurélien Bornet
Former PostDoc (2017-2018)
Permanent Position now
Nuclear Magnetic Resonance Facility Manager
EPFL Lausanne
Basile Vuichoud
Former PostDoc (2017-2018)
Permanent Position now
NMR Scientist
Firmenich - Switzerland
Stuart Elliott
Former PostDoc (2018-2021)
Permanent Position now
Deputy Nuclear Magnetic Resonance Facility Manager in the Molecular Sciences Research Hub at Imperial College London
Samuel Cousin
Former PostDoc (2017-2021)
Permanent Position now
CNRS Researcher
Aix-Marseille University
Morgan Ceillier
Former PhD Student and PostDoc (2017-2021)
Permanent Position now
Ingénieur Recherche et Développement
Capelec - Montpellier
Arianna Ferrari
Former PhD Student (interrupted PhD)
PhD Student at Kiel University / Molecular Imaging North Competence Center
Fanny Russel
Former Master II Student (2021)
Apprentie Recherche et Développement
Solvay
Paul-Emmanuel Edeline
Former Master II Student (2020)
PhD Student at Université de la Polynésie française (UPF) / Université Laval
Selected Publications
HYBRID POLARIZING SOLIDS
October 14, 2014
Proceeding of the National Academy of Science of the USA
CROSS-POLARIZATION assisted d-DNP
December 7, 2012
Journal of Physical Chemistry Letters
Selected Posters
A. Ferrari
HYP20 Conference
..about a new generation of unstructured HYPSO materials yielding >95% proton polarization...
O. Cala
HYP20 Conference
...about a hyperpolarization ready chemical library for drug screening...
T. El. Darai
HYP20 Conference
...about how porous polarizing polymers can generate transportable hyperpolarization...
Main On-going Grants
Project on Hyperpolarization Transport
ERC Starting Grant - HP4all
